Vitamin K and the Arterial Vessel Wall

Medial calcification is associated with type 2 diabetes and appears to be a strong independent predictor of cardiovascular and coronary heart disease (CHD) mortality. Calcification of the arterial media contributes to stiffening of arterial tone, which may lead to an increase in cardiac work and systolic blood pressure, a highly significant predictor of myocardial infarction and vascular death. Overall, vascular calcification maybe regarded as 1 of the major complications of cardiovascular disease and an independent risk factor for myocardial infarction and cardiac death.  ...vitamin K2 (MK-4) prevented warfarin-induced vascular media calcification.
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