Osteomyelitis antibiotics

• Gram +, co-amoyxclav, best bone penetration of penicillin
• Gram -, cipro, less chance of G+ resistance
• Biofilm, azithromycin, higher dose for Pseudomonas.spp
• Anerobics, metronidazole, low dose,
• Immunal free-nitrogen, quinine; urea, metformin, creatine

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