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Rett Syndrome April 2012

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This is in response to Rett syndrome and how to help with swallowing and breathing issues.

A short biology thought with some quick research.

In University I could never figure out why the body is so evolved and yet mixes air, food and water to complicatedly separate them just before the lungs when we can drown so quickly and die. After years of biological study I have it well sorted out.

The body is like a country. Every individual is slightly different but there are fundamental similarities between all. Every import to a country / body must pass security. This is done along the throat where food, water and air pass and are sorted completely.

The epiglottis guards the entrance of the glottis, the opening between the vocal folds. It is normally pointed upward while one is breathing with its underside functioning as part of thepharynx, but while one is swallowing, elevation of the hyoid bone draws the larynx upward; as a result, the epiglottis folds down to a more horizontal position, with its superior side functioning as part of the pharynx. In this manner it prevents food from going into the trachea and instead directs it to the esophagus, which is posterior.

The thyroid gland controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. It participates in these processes by producing thyroid hormones, the principal ones being triiodothyronine (T3) and thyroxine which can sometimes be referred to as tetraiodothyronine (T4). These hormones regulate the rate of metabolism and affect the growth and rate of function of many other systems in the body. T3and T4 are synthesized from both iodine and tyrosine. The thyroid also produces calcitonin, which plays a role in calcium homeostasis. 

If the balance of calcium in the body becomes a problem the epiglottis becomes calcified to make it stiff and slow. This is how our joints become stiff and slow but then the epiglottis allows water and food into the lungs and we develop breathing problems.

Calcitonin is a hormone that reduces calcium levels in the body.  Calcitonin (also known as thyrocalcitonin) is a 32-amino acid linear polypeptidehormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid.

More specifically, calcitonin lowers blood Ca2+ levels in three ways:


Calcitonin also up regulates vitamin D which has the effect to:
  • Inhibits phosphate reabsorption by the kidney tubules[10]
  • Decreases tubular reabsorption of Ca2+, leading to increased rates of its loss in urine.[11]

Other effects are in preventing postprandial hypercalcemia resulting from absorption of Ca2+.

 

In summary the thyroid blocks absorption of calcium from food, displaces calcium away from the epiglottis and causes the kidney to expel more calcium to lower blood levels. It also up regulates osteoclast activity at the bone which keeps calcium in bones and not in the blood. Taking a calcium supplement destroys the bodies ability to clear calcium and we have swallowing and breathing diseases later.

 

Calcium manipulation in the body is highly controlled by vitamin K. This is the counter vitamin to D where D helps to get rid of calcium whereas K holds it in the body along the surfaces of the bones and teeth but protecting the soft tissues from overload. Vitamin K is held along the arteries and veins so that as soon as blood is leaked it coagulates (K-German Koagulation, C-Coagulation) to stop bruising and bleeding. Low levels of K are associated with bone loss (osteopenia) and bone pains. Prevention of bone fractures can be done with K and all autistic children have low levels of K.

 

 

Vitamin K deficiency appears to play a role in the development of osteoporosis

and in the deposition of calcium into blood vessels.7,8   Calcification of the

arteries,  known as “arteriosclerosis,” contributes to heart attacks and strokes.

 

 

• Vitamin K, an anti-oxidant that is more powerful than Vitamin E or CoQ10, is

able to potently inhibit glutathione depletion-mediated oxidative cell death. 9,10

• Vitamin K inhibits production of Interleukin-6, an inflammatory cytokine. 11

• Vitamin K is found in high concentration in the pancreas and appears to be

involved in controlling blood sugar. 12

• Vitamin K is involved in the development of the nervous system. 13 Page 1 of 15

• Vitamin K has a role in glutamate conversion 14  and its absence affects the rate of

activity of the enzyme glutamate dehydrogenase 15.

 

Who should take Vitamin K supplements?
Pregnant women,mum and baby id 16233
new born infants,
breast fed babies,

 

Merck Manual:

 

Worldwide, vitamin K deficiency causes infant morbidity and mortality. Vitamin K deficiency causes

hemorrhagic disease of the newborn, which usually occurs 1 to 7 days postpartum. In affected neonates,

birth trauma can cause intracranial hemorrhage. Neonates are prone to vitamin K deficiency because of the following:

 The placenta transmits lipids and vitamin K relatively poorly.

 The neonatal liver is immature with respect to prothrombin synthesis.

 Breast milk is low in vitamin K, containing about 2.5 μg/L (cow's milk contains 5000 μg/L).

 The neonatal gut is sterile during the first few days of life.

 

The Symptoms and Signs:

 

Hemorrhagic disease of the newborn and late hemorrhagic disease in infants may cause cutaneous, GI, intrathoracic, or, in the worst cases, intracranial bleeding (bleeding in the brain in the first few days of life).

 

What can cause a vitamin K deficiency:

 

  • megadoses of vitamin E

 

Which some pregnant women use to reduce skin stretch marks.

Wikipedia: vitamin E:

A Japanese study in 2012 found that vitamin E may contribute to osteoporosis.[15]

This would make sense because vitamin E reduces vitamin K which keeps bones healthy.

Vitamin E refers to a group of eight fat-soluble compounds that include both tocopherols andtocotrienols.[1] There are many different forms of vitamin E, of which γ-tocopherol is the most common in the North American diet.[2] γ-Tocopherol can be found in corn oil, soybean oil, margarine and dressings.[3][4] α-Tocopherol, the most biologically active form of vitamin E, is the second most common form of vitamin E in the North American diet. This variant of vitamin E can be found most abundantly in wheat germ oil, sunflower, and safflower oils.[4][5] It is a fat-solubleantioxidant that stops the production of reactive oxygen species formed when fat undergoes oxidation.[6][7][8]

Reactive oxygen species is another name for nitric oxide and this molecule is key for the immune system to kill bacteria, fungi, parasites, viruses and tumors. By taking vitamin E we reduce our immune system and one possible result is Rett Syndrome in newborn babies.

 

At the beginning I had no idea where this would take me but here it is.

 

Suggestions for Rett problems:

1. Salmon Oil, not wild blends of fish oils, just and only salmon oil, this is hard to find, check our product list at www.reboundhealth.com Salmon is a good source of calcitonin.

2. Thyroid testing.
3. Glutathione, oral works well contrary to whatever you read, protects the nerves
4. MSM, keeps the epiglottis flexible and functioning. protects the lungs
5. Vitamin K3 - menadione, a short description of the types.
6. No raw food that is full of bacteria, fungi and viruses. Only cooking kills germs.
7. No dairy, no skim milk , no milk, no yogurt, just don't do it; butter is good.
8. No ensure, No pediasure, No processes cold liquid junk food.
9. Peanut butter
10. mashed potato
11. Warm coffee or warm cocoa. (early in the day, not before sleep time)
12. Scrambled egg, whole egg with the yolk
13. White rice with butter, salt and some black pepper. The black pepper is known to clear the throat and rebuild brain cells. Here is the food cocktail for Alzheimer's Dementia.
14. No Soy, No Fruit, No Soy, No Fruit, No Soy, No Fruit. These destroy brain cells.
This means NO Tofu, and ZERO SOY, not even the amount in soup cubes or soup stock. Make your own soup from scratch.
I hope this helps, Let me know,
Cheers,
Bryon

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