Topic: Pathogens

Respiratory problems are often caused by a limited group of pathogens that can be inert molecules like a gas but recurring problems are most often associated with bacteria, virus and fungi.  Newer testing is finding some viruses to be the DNA of fungi like the spores of a mushroom as a mechanism to spread through the environment.  Air conditioners will concentrate moisture from cooling the air and increased humidity are contributing factors to an increase of pathogens in the air.  The overload of the respiratory system can bring on a flare up while the underlying cause has remained in the respiratory pathway.  Household members can also be a source for flare-ups and may not actually have symptoms.

The chronic nature of these pathogens lies in their ability to protect themselves in all phases of their life.  These phases include reproducing, growing, spreading, hibernation and die-off.   A free swimming or a new colonization is when the pathogen is most vulnerable and this is when antibiotics are most effective.  This can be the acute phase when we might have the most symptoms.

If there is prolonged exposure to an antibiotic some can convert to a dwarf from where one normal cell contains tens of thousands of very small bacteria and then they explode to travel through the body and tissues like a virus.  When disbursed they only expand where and when the antibiotic is low or not present. 

Another trick to protect themselves is to convert the normal binding site of the antibiotic to a non-binding site.  This is like insulin resistance where the molecule (penicillin) just stops working.  In staph this is seen with MRSA: Methacillin Resistance Staph Aureus, one of the most deadly bacteria in that it can coagulate blood and stop blood flow to a tissue.

To combat these adaptations there is a process called physiologic conflict where a drug that forces the bacteria from a dormant phase into a growth phase is combined with a drug that kills them while growing and another drug that forces them to not become dwarf forms or dormant.  This process can be species specific, detailed, and highly complex.  A lab test to grow or amplify the pathogen will produce the most prolific or dominant one while an old infection is most often multi-pathogenic.  In some cases the most dominant pathogen is kicked out, but another aspect of microscopic life is the ability of one species to teach a completely different organism how to produce protective enzymes that counter the immune system.

The approach of Western medicine is to treat the symptom of the problem as it re-appears and name it an “auto-immune disease”.  Often there is a comment in the larger medical text books stating that most patients are not willing to go through what it would take to eradicate the pathogen.  There is mention that more are satisfied with the practitioner to simply deal with the symptoms for a symptomatic relief.  From this we have developed wide spread use of the terms allergy and auto-immune as accepting recurrent problems. 

An approach would be to cover as many possible pathogens in as many of their physiological states as possible.  A step in approach with the agents would help to stagger die-off and weaken the pathogens systematically in preparation for the next agent.  Some agents are not effective because the pathogens are able to convert physiological states rapidly.  In one study an E.coli  colony became resistant to an agent in twenty minutes. 

Our goal would be to push the pathogens into a specific physiological state and then introduce an agent that is effective while in this state.  If they try to revert to the first state we know that the first agent is in sufficient concentration to harm them.  Then they will likely convert to the dormant phase and then we introduce another agent that strips them of their protective barrier and either the immune system kills them or a different agent that harms them if they pass into any other protective phase.

Sometimes this can be done with two agents and may include things like table salt and iodine.  Vinegar and vitamin C are also good agents with the later known to help in respiratory problems.  Inhaling vaporized table salt and taking an agent that has no activity in the lab is working on cystic-fibrosis patients.  This even works when they have the extremely pathogenic and chronic pseudomonas aureginosa combined with staph aureus.  In the past this was considered untreatable.

This is not intended to make any claim nor is it intended to be a diagnosis.  It is my opinion. -- Bryon